How the CIA Creates Mind Controlled Assassins
American Alchemy with Jesse Michels
It's a movie from 1961 with Frank Sinatra and it discusses the creation of this assassin essentially post Korean War...It's based on a book from the 50s.
2 podcast mentions
The Manchurian candidate
Sgt Raymond Shaw is a hero of the first order. He's an ex-prisoner of war who saved the life of his entire outfit, a winner of the Congressional Medal of Honor, the stepson of an influential senator...and the perfect assassin. Brainwashed during his time as a POW he is a 'sleeper', a living weapon to be triggered by a secret signal. He will act without question, no matter what order he is made to carry out. To stop Shaw, his former commanding officer must uncover the truth behind a twisted conspiracy of torture, betrayal and power that will lead to the highest levels of the government...
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Dr. Colin Ross | MKULTRA, Manchurian Candidates, & the CIA’s Darkest Experiments
There is a book in the 1950s or 1960s somewhere in there that was published and then the movie starring Frank Sinatra, The Manchurian Candidate, less than 10 years later, and then there's a remake with Denzel Washington.